Just one dose of RUCONEST can get you back to things that matter

  • 97%One and Done – 97% of acute swells were treated with JUST 1 DOSE*
  • 93%Relief That Lasts – Stopped 93% of attacks for at least 3 days†
  • 85%Confident Dosing – 85% of patients were confident self-administering‡

How RUCONEST is helping Sophie manage her swells

*50 U/kg (max 4200 U) in clinical studies (open-label extension phase, n=44 [170 attacks]).
†As shown in a review of studies that included 68 people (280 attacks).
‡Data from 601 patients using RUCONEST show that 85% of patients trained felt confident, mostly confident, or extremely confident on a Likert scale of 1-5 in terms of their ability to self-infuse.

Experience the benefits of one-and-done dosing with RUCONEST

If you are treating the same swell multiple times, speak to your doctor about a change. RUCONEST may be able to help you get back to things that matter. RUCONEST replaces the missing or nonworking C1-INH to stop an HAE swell.
HAE attack symptom: fatigue
  • 9 of 10 patients achieved symptom relief in the pivotal clinical trial with just 1 dose (n=44)*
  • In the primary clinical study, patients saw symptom relief in 90 minutes vs 152 minutes with placebo*
  • In the extension study, symptom relief began in 75 minutes*

*50 U/kg (max 4200 U) in clinical studies (open-label extension phase, n=44 [170 attacks]).

RUCONEST offered relief that lasts

Your acute treatment should work with just 1 dose and provide you relief that lasts.
HAE attack symptom: fatigue
*As shown in a review of studies that included 68 people (280 attacks). Based on a post hoc analysis of pooled data from the randomized controlled study and open-label extension phases of 2 studies involving 127 patients aged 13 years who were treated with RUCONEST 50 U/kg (max 4200 U) for acute attacks of HAE. Data for 72 hours were available for 68 of 127 patients.

RUCONEST has a well-established tolerability profile

RUCONEST has a well-established tolerability profile. Adverse reactions in ≥2% of patients in 7 studies (all RUCONEST doses up to 100 U/kg) included:

HAE attack symptom: fatigue

Headache9% (19 of 205 patients)

HAE attack symptom: fatigue

Nausea2% (5 of 205 patients)

HAE attack symptom: fatigue

Diarrhea2% (5 of 205 patients)


You can confidently administer RUCONEST

Confidently administer RUCONEST after training
  • RUCONEST is portable and can be self-administered after training*
  • Prior to reconstitution RUCONEST does not need to be refrigerated
  • After reconstitution, RUCONEST is injected over 5 minutes with a small butterfly needle

*Initial training will be under the supervision of an HCP experienced in the treatment of HAE.

†Data from 601 patients using RUCONEST show that 85% of patients trained felt confident, mostly confident, or extremely confident on a Likert scale of 1-5 in terms of their ability to self-infuse.

See the vein finder in action

Talk with your healthcare provider about RUCONEST

Be prepared for your next office visit. Print this helpful guide.

"Having a list of questions to ask my doctor helps me feel more empowered to understand and take control of my HAE."

— Corey, living with HAE

RUCONEST information and contact form

HAE is a rare disease – but you are not alone. Getting connected with you matters to us. That’s why we provide support for your HAE journey every step of the way. Get in touch!

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