What is HAE and what are the signs of an HAE swell?

  • HAE is a rare condition that causes repeated episodes of swelling
  • Not an allergy or allergic reaction
  • May be inherited but can also occur without any family history
  • Signs vary from person to person but may include those shown here. For best results, treat at the first sign or symptom of a swell.

Your healthcare provider can confirm an HAE diagnosis based on the results of a blood test. Be prepared for your next healthcare provider visit by downloading a helpful discussion guide.

Download Discussion Guide

What events can trigger an
HAE swell?

Even though swells may occur without a clear trigger, it's important to recognize some common triggers that can lead to an attack, such as:

  • Anxiety
  • Stress
  • Minor injuries
  • Dental procedures
  • Medications
  • Infections
  • Hormonal changes, such as those occurring during pregnancy or menstruation

“I've learned what to look for, so that I can anticipate when an attack is about to happen.”

— Corey, living with HAE

Create a treatment plan with
your healthcare provider

Even if you are taking preventitive treatment, you should always have at least 2 doses of on-demand treatment on hand at all times to treat HAE swells when they occur.

Bring this guide to your next healthcare appointment.

Download Discussion Guide

“Having a list of questions to ask my doctor helps me feel more empowered to understand and take control of my HAE.”

— Corey, living with HAE

Symptom relief with just 1 dose

“If I do get an attack, I can rely on RUCONEST to treat my swells.”

— Gloria, living with HAE

Relief that lasts

  • As shown in a review of studies that included 68 patients (280 attacks)

Do not use RUCONEST if you have experienced life-threatening immediate hypersensitivty reactions, including anaphylaxis, to RUCONEST or to any other C1-esterase inhibitor (C1-INH) product. Call your healthcare professional or the emergency department right away if you experience: wheezing, difficulty breathing, chest tightness, turning blue (look at lips and gums), fast heartbeat, swelling, faintness, rash or hives.

The most common side effects patients experienced during clinical studies include headache, nausea and diarrhea.
These are not all the possible side effects of RUCONEST.

Keep your HAE swells grounded with RUCONEST

97% of attacks needed JUST ONE DOSE†

Symptom relief lasted for at least 3 days in 93% of attacks‡

RUCONEST can be self-administered

RUCONEST is PLASMA-FREE—so there is no risk of passing on human viruses

Most common side effects included headache, nausea and diarrhea †

†As shown in clinical trials.

‡As shown in a review of studies that included 68 patients (280 attacks).